Электронномикроскопические изменения альвеолярных макрофагов респираторного отдела легких в динамике после экспериментальной термической травмы

Аннотация

In experiment on white rats studied submicroscopic state of respiratory part of alveolar macrophages of the lungs in the stage of shock, early and late toxemia, septicotoxemia after thermal trauma, ІІІ degree. In the early stages of the experiment (1, 7 days) it was revealed reorganization of macrophages, indicating their increased functional activity. Submicroscopically is this reflect in increase of the number and size of microvilli and invagions of plasmolemma, primary lysosomes and phagosomes. In later stages, significant changes of ultrastructure of most macrophages, occur they have much less microvilli have picnotic nuclei and destructively damaged organelles in their cytoplasm and accumulation of secondary lysosomes. This is due to the influence of thermal pathogenic factor