MICROBIAL LANDSCAPE OF THE ENDOMETRIUM IN PATIENTS WITH CHRONIC ENDOMETRITIS.

Аннотация

The aim of the study was to investigate the microbiological features of chronic endometritis (CE) in women of reproductive age. A total of 76 patients with histologically confirmed CE were examined, divided into two groups according to the degree of inflammation activity. Real-time PCR with the Femoflor-16 kit was used to analyze the endometrial microbiota. In patients without CE, the microbiota was predominantly represented by Lactobacillus spp. (85.0%) and Eubacterium spp. (60.0%). In moderate CE, Streptococcus spp., Staphylococcus spp. and Enterobacteriaceae spp. were detected more often, while associations of Mobiluncus spp./Corynebacterium spp. and Gardnerella vaginalis/Prevotella bivia/Porphyromonas spp. were less common (p < 0.05).