MEDICINAL OF PLANTS CHRONIC IN CHOLECYSTITIS IMPORTANCE

Аннотация

This of the disease polyethological and pathogenesis mechanisms abundance him/her to correct various approaches demand does . Such without , naturally come output components own inside received herbal remedies main therapy with together separately attention is worthy . Curcumin farnesoid X receptor through from cholestasis protection to the effect yes , this bile acid homeostasis to restore and inflammation reactions against to stand and as a result cholestasis to decrease take comes . One row research this showed that curcumin grass bubble reduction to the ability has . Many numerical various kind useful features to the existence despite the fact that curcumin medical in practice wide application close until then with its low bioavailability limited was . Kavacurcumin such as biological existence high was forms synthesis made from ex . use Grass roads and stomach under diaper pathology modern medicine for current is a problem . The last ten annually Pharmacological research both in Uzbekistan and abroad at the market food digestion to do system functional violations correction for new effective medicine of tools appearance to be with related known therapeutic to success despite the disease increase trend being observed . biliary from the system . From this except this trend stability with separated It stands . So scientific to forecasts according to , the next 15-20 years inside food digestion to do system diseases stress, dyskinetic , metabolic in the world to diseases based diseases number increase on account of at least 30-50% increases . mechanisms . There are chronic acalculous cholecystitis and chronic calculous cholecystitis. Currently, the prevailing opinion is mainly about the progressive development of gallbladder diseases. Functional motor-tonic 94 MODELS AND METHODS IN MODERN SCIENCE International scientific-online conference disorders ( dyskinesia ) of the biliary tract, respectively, of a hyperkinetic (hypertensive) or hypokinetic (hypotonic) type, occur with an increase or decrease in tone. contractile (motor) activity of the gallbladder, often contributing to stagnation, changes in physicochemical properties and infection of bile in the gallbladder. A chronic inflammatory process develops, affecting its mucous membrane and wall. In most cases, the formation of cholesterol, bilirubin and mixed gallstones occurs, often accompanied by stony cholecystitis, which is often diagnosed with gallstone disease . In most cases, it develops against the background of a bacterial infection that enters the gallbladder by enterogenic (ascending from the intestine), hematogenous (from foci of chronic infection) or lymphogenous route. The development of the disease is facilitated by stagnation bile in the gallbladder, mainly due to hypokinetic biliary dyskinesia, anomalies in their development, a sedentary lifestyle (inactivity), errors in nutrition (excessive consumption of fats and fried foods, easily digestible carbohydrates, insufficient consumption of vegetable fiber, etc.), rare meals, obesity, repeated pregnancies, constipation, etc. In the initial stage of chronic cholecystitis, the inflammatory process, initiated by bacterial and other flora, affects the mucous and submucosal membranes of the gallbladder. In the future, inflammatory infiltration spreads to the entire gallbladder wall with the development of connective tissue (fibrosis) and thickening of its wall; damage to the serosa. The clinical picture of chronic cholecystitis consists of pain, dyspeptic and neurotic syndromes. The nature of the pain depends to some extent on dyskinesia of the common bile ducts: in the hypotonic variant it can be constant or periodic, dull or aching, in the case of hypertension - short-term, more intense, cramping. The pain is localized in the right hypochondrium and epigastric region and can radiate to the right shoulder blade, collarbone, shoulder and lumbar region. With the above-described irradiation, unbearable, very strong, cramping pains in the right hypochondrium - biliary colic - are characteristic of HCG and often occur as a result of blockage of the gallbladder neck or extrahepatic bile ducts with stones. The pain syndrome is provoked by the consumption of fatty, fried, smoked, spicy foods, carbonated drinks; heavy physical exertion (lifting and lifting heavy loads, physical exercises with a bent torso, etc.), body shaking (riding in shaking vehicles, etc.), psychoemotional stressful situations. Dyspeptic syndrome is characterized by nausea, belching, bitterness in the mouth, bloating, stool disorders (constipation or diarrhea) and decreased appetite. Vomiting is very rare. Typical manifestations of neurotic syndrome - conflict, inconsistency and a tendency to introspection. When 95 MODELS AND METHODS IN MODERN SCIENCE International scientific-online conference examining the patient, it is often found that the sclera is subicteric and the tongue is superimposed. With the help of palpation and percussion