IMMUNOHISTOCHEMICAL CHANGES IN THE LUNGS AFTER LOCAL AND GENERAL ANESTHESIA IN EXPERIMENTAL MECHANICAL TRAUMA

Аннотация

Many authors have assessed the effective action of isoflurane using an ischemic pulmonary model with ex vivo reperfusion [13]. Based on these actions, researchers have concluded that when preliminary preconditioning with isoflurane occurs, vascular resistance indicators increase and pulmonary tissue edema. The authors performed a comparative assessment of sevoflurane and isoflurane in terms of their effect on reducing ischemic and reperfusion injury to lung tissue, and found that a single inhalation at a minimum alveolar concentration 30 minutes before ischemic reperfusion with any anesthetic resulted in a decrease in lung injury biomarkers in an ex vivo model [13–15].