Уровень медиаторов иммунного ответа у детей с эпилепсией на фоне церебрального паралича

Аннотация

A study of 85 children with epilepsy or without at cerebral palsy background to study the level of pro-inflammatory (TNF-α and IFN-γ) cytokines in the serum and cerebrospinal fluid. It was revealed that the pe-ripheral blood serum of children with cerebral palsy TNF-α level by almost 3 times higher than control group values, and IFN-γ level is 1.3 times lower than control values. In children with cerebral palsy with epilepsy on a background level of TNF-α is 1.5 times higher than the control group values, and 1.7 times lower than that of children with cerebral palsy without epilepsy, and the level of IFN-γ in the presence of epilepsy is 1.7 times lower control values. In the cerebrospinal fluid of children with cerebral palsy and epilepsy level of TNF-α was significantly higher than in children without epilepsy