Изучение спектра противо- и провоспалительных цитокинов в сыворотке крови при семейной бронхиальной астме

Аннотация

The article considers the spectra of anti- and proinflammatory cytokines in blood serum at the family bronchial asthma, as well as the nature of clinical and pathogenic forms of bronchial asthma, which affect the formation of the disease. The study was conducted in 346 relatives from 49 families with bronchial asthma. It was determined in the serum of IL-6 and γ-interferon that the "Vector-Best" test was used. A study was made of the number of IL-6 and γ-interferon in the blood serum in patients with familial bronchial asthma, depending on the pathogenetic forms, stages, length of service and the degree of disease control. It was found that an in- crease in the number of IL-6 in the blood serum, a decrease in interferon-γ depending on the stage, allergic forms, an increase in the length of the disease and in patients with uncontrolled asthma are a differential diag-nostic marker.