DETERMINATION OF THE ACUTE TOXICITY OF WILD PEAR (PYRUS PYRASTER) DRY EXTRACT

Аннотация

As is known from the literature, the fruit of pear (Pyrus communis) has been used as food since ancient times. There are more than 22 species of it, one of which is the wild pear, which is the ancestor of the modern cultivated pear. Diabetes mellitus remains one of the most urgent problems of clinical medicine. Diabetes mellitus is the third leading cause of death from this disease (6%), after cardiovascular diseases (51%) and cancer (17%). Over the past 10 years, the incidence of diabetes mellitus has increased in all countries of the world. Children under the age of 14 account for 6-8% of the population with diabetes. The annual increase in the number of children with insulin-dependent diabetes is 6%. Up to 13% of children with diabetes are under the age of 5. Due to the high content of beneficial substances in the composition of wild pear, it has been used: for diuretics, inflammation, normalization of blood pressure, and boosting immunity. Scientific research in recent years has shown that natural compounds consisting of polyphenols and polysaccharides in their chemical composition are used to prevent the development of obesity and diabetes (by reducing the amount of glucose in the blood).