Prevention Of Premature Skin Aging Through the Use of Bioactive Forms of Vitamin C With Hyaluronate

Аннотация

Premature skin aging is a complex, multifactorial process that results in structural and CITATION Uliana-Sofiia Savchenko. (2025). Prevention Of Premature Skin Aging functional alterations of the skin. It is characterized as Through the Use of Bioactive Forms of Vitamin C With Hyaluronate. The an accelerated aging process triggered by both American Journal of Medical Sciences and Pharmaceutical Research, 7(8), 51–55. https://doi.org/10.37547/tajmspr/Volume07Issue08-08 endogenous and exogenous factors. The primary pathogenetic mechanism underlying premature skin COPYRIGHT aging is the formation of oxidative stress induced by © 2025 Original content from this work may be used under the terms of the creative commons attributes 4.0 License. ultraviolet (UV) radiation. This leads to the generation of reactive oxygen species (ROS), which oxidize lipids, inactivate components of the extracellular matrix, and degrade collagen, elastin, and hyaluronic acid, as well as cause direct DNA damage. The purpose of this study is to systematically analyze scientific data on the effects of bioactive forms of vitamin C, hyaluronate, and their combination on the processes that contribute to premature skin aging. The findings confirm that the antioxidant properties of bioactive vitamin C, combined with the hydrophilic environment created by hyaluronate in the extracellular matrix, have a beneficial effect in preventing premature skin aging. However, the potential for their synergistic interaction requires further investigation. Keywords: vitamin C, hyaluronic acid, hyaluronate, antioxidants, oxidative stress, skin aging, photoaging, extracellular matrix, collagen, ultraviolet radiation.