THE EFFECT OF STORAGE AND TRANSPORTATION CONDITIONS OF DRIED BLOODSTAIN SAMPLES TAKEN FOR THE DIAGNOSIS OF FABRY'S DISEASE ON THE RELIABILITY OF SCREENING RESULTS

Аннотация

In modern laboratory diagnostics, various technologies are used to analyze blood samples. Among them, the use of dried bloodstain (DBS) samples has advantages: they are easy to assemble, easy to transport and store for a long time. However, the reliability of the DBS sample analysis results is directly related to how they were stored and under what conditions they were transported [1,2,3]. This paper will consider the conditions for maintaining the stability of DBS samples and their impact on the results of screening tests. DBS samples are bloodstains dripping and dried on special filter paper, which are mainly used in infant screening, infectious disease diagnosis, and pharmacokinetic studies. This method increases safety when working with biomaterials and simplifies logistics. However, storage and transportation of DBS samples directly affect the reliability of the analysis results [4,5].