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РецензированоEN2025

REPRODUCTIVE AND DEVELOPMENTAL EFFECTS OF A THYROTROPIC EXTRACT FROM POTENTILLA ALBA IN MALE RATS

MALE RATS (AN D INNOVATION IF = 5.28 1 www.in-academy.uz) · Komiljonova Oygul Olimjonovna (AN D INNOVATION IF = 5.28 1 www.in-academy.uz) · KEY WORDS (AN D INNOVATION IF = 5.28 1 www.in-academy.uz)

Центральноазиатский журнал образования и инноваций · 4 · 2025

Аннотация

Background: The dysfunction of the thyroid gland is a common medical condition. Nowadays, patients frequently use medicinal herbs as complementary or alternative options to conventional drug treatments. These patients may benefit from treatment of thyroid dysfunctions with Potentilla alba L. preparations. While it has been reported that Potentilla alba preparations have low toxicity, nothing is known about their ability to affect reproductive functions in patients of childbearing age.

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«Background: The dysfunction of the thyroid gland is a common medical condition.»

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Background: The dysfunction of the thyroid gland is a common medical condition. Полный текст публикации CiteX не хранит — доступ к первоисточнику открывается по DOI согласно лицензии издателя и выбранному плану.

doi.org/10.5281/zenodo.15523630
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alternative options to conventional drug treatments, we report that oral treatment of male Wistar rats with PADE before mating with intact females instigated marked effects on male reproductive organs. Treatment significantly decreased the motility of the sperm and increased the number of pathological forms, a dose-dependent effect on Leydig cells was observed. However, Herein, these PADE effects did not significantly affect male fertility nor fetal and offspring development when PADE-treated males were mated with intact females.
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