DIFFERENTIAL DIAGNOSTICS OF NON-SPECIFIC INTERSTITIAL PNEUMONIA

Аннотация

Purpose of the study. Determination of differential diagnostic signs of nonspecific interstitial pneumonia and other lung diseases. A retrospective analysis of case histories of 82 patients with nonspecific interstitial pneumonia, 24 patients with idiopathic pulmonary fibrosis, 8 with exogenous allergic alveolitis, 12 with systemic scleroderma and 6 with drug pneumonia was carried out in hospital treatment in the pulmonology department of the Samarkand city medical hospital. All patients underwent the required number of examinations using clinical and laboratory methods, as well as radiography and high-resolution computed tomography. Research results show that the clinical course of nonspecific interstitial pneumonia is similar to the course of idiopathic pulmonary fibrosis, exogenous allergic alveolitis, systemic scleroderma and drug-induced pneumonia. Tomographic signs of nonspecific interstitial pneumonia - “ground glass”, predominantly basal localization, symmetrical subpleural zones of preserved parenchyma, moderate reticular changes; with idiopathic fibrosis - “honeycomb lung”, clear reticular changes with subpleural and basal localization; with exogenous allergic alveolitis - “ground glass”, unaffected subpleural lines (subpleural sparing), equal distribution, including the upper lobe, areas of reduced transparency; intralobular nodes; in a chronic course - thickening of the subpleural “honeycombs”, interlobular and intralobular walls; with systemic scleroderma - dilation of the esophagus along with dilation of the pulmonary artery, similar to nonspecific interstitial pneumonia; for drug-induced pneumonia - the same as for nonspecific interstitial pneumonia. It has been established that in the differential diagnosis of nonspecific interstitial pneumonia and other lung diseases, particular attention should be paid to the anamnesis, clinical presentation and CT signs.