BIOCHEMICAL FACTORS OF THE DEVELOPMENT OF COGNITIVE IMPAIRMENT IN PEOPLE WHO HAVE UNDERGONE COVID-19

Аннотация

Coronavirus infection (COVID-19) is an acute infectious disease caused by a new strain of SARSCoV-2, which is pathogenetically characterized by viremia, local inflammatory process, systemic immune inflammation, as well as activation of the hypercoagulation process, endothelial dysfunction, hypoxic disorders, which leads to an increase in the process of thrombosis, at the same time, it can be asymptomatic or with signs of intoxication, fever and multiple organ damage, followed by neurological disorders and the risk of complications. The most common symptoms of nervous system damage were headache, asthenia, loss of sense of taste and smell , tinnasit, anxiety, depression, and cognitive impairment which is related to memory and attention. Damage to the nervous system confirms the neurotropism of the COVID19 virus and the presence of neuroinflammatory syndromes. The most discussed issue is the question of the genesis of cognitive impairment after COVID19. There are many publications in the literature on the exacerbation of existing cognitive disorders in the elderly (2-4). But there are not enough work on the genesis of cognitive disorders in young, previously healthy individuals. Our task was to study this issue.