SIGNIFICANCE OF IMMUNOLOGICAL BIOMARKERS IN THE DEVELOPMENT OF NONSPECIFIC INTERSTITINAL PNEUMONIA

Аннотация

The article is devoted to the significance of the content of neutrophil elastase and interleukins (IL-1b, IL-17A) in the blood of patients with nonspecific interstitial pneumonia. The regulation of the inflammatory response in nonspecific interstitial pneumonia depends on a complex interaction between immune cells and inflammatory-specific and anti-inflammatory cytokines. Enzymes of proteolysis (neutrophil elastase) can serve as a diagnostic marker that determines the severity of nonspecific interstitial pneumonia. In nonspecific interstitial pneumonia, disturbances are noted in the form of a change in the concentration of interleukins - IL-1β, IL-17A in the blood serum of immunocompetent cells of the peripheral blood flow. Changes in the concentration of cytokinins and neutrophil elastase indicate a correlation with the severity of the disease.