FEATURES OF CHANGES IN THE MICROFLORA OF THE VAGINA TO WOMEN

Аннотация

Our body is inhabited by a large number of microorganisms. They live on the skin, in the mucous membranes of the mouth and nose, in the intestines, and in women and in the vagina. The vagina is covered with a multi-layered non-corneating squamous epithelium, which does not contain glands. [1,2,3,7,8]. The processes of physiological maturation of the cells of the vaginal mucosa, their peeling and the thickness of the surface layer are subject to cyclic changes in response to the action of sex hormones. [5,6]. The epithelium of the vagina, performing a protective function, ensures its resistance to the effects of pathogenic agents (bacteria, viruses, fungi). An important indicator of the resistance of the vaginal epithelium is the amount of glycogen, which is contained mainly in surface cells. Since these cells are constantly being exfoliated and destroyed, glycogen is released, providing a nutrient substrate for normal microflora. The amount of glycogen in the cells of the vaginal epithelium varies in the same woman throughout her life, as well as depending on the phase of the menstrual cycle. The maximum accumulation of glycogen occurs at the time of ovulation. [2, 7]. The vaginal microflora is strictly individual and may even be subject to changes in different phases of the menstrual cycle in a normal state. In addition, the concept of norm can be different for different age groups, ethnic groups and even geographical zones. In this regard, variants of normal microbiocenosis (normocenosis) of the vagina are possible [8,10].