CLINICAL AND ANAMNESTIC RISK FACTORS FOR THE DEVELOPMENT OF SYMPTOMATIC EPILEPSY IN INFANTILE CEREBRAL PALSY

Аннотация

Cerebral palsy (CP) is a non-progressive disease associated with a predominant impairment of the child's motor development. Symptomatic epilepsy (SE) accompanies cerebral palsy, which complicates the course of the disease. Risk factors and morpho-functional changes, which serve as the basis for the formation of SE in cerebral palsy, have not been sufficiently studied. We examined 308 children with cerebral palsy at the age of 1 to 16 years and their mothers by questioning them. Patients with cerebral palsy, depending on the presence or absence of SE, were divided into 2 groups. I group – 114 children, II group – 194 children, respectively. It was revealed that the main role in the development of SE in cerebral palsy is played by concomitant extragenital diseases and maternal intoxication during pregnancy, as well as the totality of all prenatal and natal factors. For children with cerebral palsy, who had hereditary and perinatal factors, it is advisable to prescribe GABA-ergic drugs, and in cases of SE debut, start early anticonvulsant therapy.