ESTIMATION OF THE SIGNIFICANCE OF POLYMORPHIC ALLELIC VARIANTS OF GENES OF THE HEMOSTASIS SYSTEM VEGFα IN THE DEVELOPMENT OF CEREBVASCULAR DISORDERS

Аннотация

Metabolic syndrome - a condition that represents a combination of several factors (hyperinsulinemia, hypertension, dyslipidemia, obesity), which greatly increases the risk of cerebrovascular diseases. In our study, we examined patients with ischemic stroke in the acute phase of the disease - 96 people with metabolic syndrome and without it. It was found significant differences in genetic status in patients with metabolic syndrome on the background with acute ischemic stroke. Alleles and genotypes of the rs2010963 (-634G>C) polymorphisms of the gene (VEGFs) were studied in patients with ischemic stroke with metabolic syndrome and without it;