FEATURES OF IMMUNOLOGICAL INDICATORS IN PATIENTS WITH CHRONIC OBSTRUCTIVE LUNG DISEASE AND BRONCHIAL ASTHMA

Аннотация

The study was conducted in the Samarkand city hospital in the department of pulmonology. The study included 103 patients. Patients, depending on the presence of pathologies, were divided into three groups. The first group consisted of 37 patients with chronic obstructive lung disease, the average age of which was 48.3 ± 1.7, the second group consisted of patients with a diagnosis of bronchial asthma, there were 36 patients (average 44.7 ± 1.5) and 30 healthy people that made up the control group. The results of the study showed that, with chronic obstructive lung disease and bronchial asthma, changes in the immune system occur, which differs significantly from each other, primarily due to a significant increase in the content of cytotoxic lymphocytes in the blood of patients with chronic obstructive lung disease. It can be assumed that it is the high cytotoxic potential of the immune system of patients with chronic obstructive lung disease that causes damage to the lung tissue, causing the development of pneumosclerosis and pulmonary emphysema.