COMPREHENSIVE RISK ASSESSMENT OF THROMBOCYTOPENIA IN ONCOLOGY PATIENTS: FROM PREDICTORS TO PERSONALIZED THERAPY

Аннотация

The presented study focuses on a multi-parametric risk assessment of thrombocytopenia in an oncology cohort using modern diagnostic methodologies. A comprehensive prediction algorithm has been developed, integrating clinical, laboratory, and molecular genetic predictors. The article aims to systematize diagnostic approaches to assessing thrombocytopenia risk from a multifactorial analysis perspective in palliative oncology. The paper presents a conceptual approach that includes quantitative assessment of baseline platelet reserve, analysis of genetic predisposition, evaluation of platelet functional potential, and molecular genetic risk stratification.