EXOGENOUS AND ENDOGENOUS FACTORS IN THE PATHOGENESIS OF BENIGN SALIVARY GLAND TUMORS

Аннотация

This article examines the main exogenous and endogenous factors contributing to the development of benign salivary gland tumors. The influence of genetic predisposition, mutations in oncogenes, and tumor suppressor genes is analyzed. Adverse external influences, including industrial and environmental factors, occupational hazards, unhealthy habits, and infectious agents, are considered. Special attention is given to the role of the Epstein-Barr virus and other pathogens in tumor progression. The identified mechanisms provide a deeper understanding of the pathogenesis of these neoplasms and outline promising directions for prevention and early diagnosis.