CHANNELOPATHIES IN THE GENESIS OF INTELLECTUAL DEVELOPMENTAL DISABILITY IN CHILDREN WITH EPILEPSY

Аннотация

Epilepsy and intellectual/developmental disabilities still be the most common disorders in pediatric neurology [1; 6]. Those conditions often occur together, that is why we need to exclude their common pathogenetic basis [8; 4; 9]. Psychomotor development and intelligence are targets for intractable seizures, their chronic blow leads to the hard cognitive and social disability [3; 7]. The target group of this study is a child population, with age period from 0 to 7 years. The common feature of the study group is the early age of disease manifestation (from 1 to 2 years of age). It is the period of the maximum formation of the central nervous system and all vital skills. Any pathology during this period leads to inevitable destructive processes in the central nervous system. It is extremely important to provide assistance during this period, when the process of negative impact on development can be reversible.