SOCIAL AND CLINICAL-BIOCHEMICAL FACTORS IN THE PATHOGENESIS OF GASTRITIS AND ULCER DISEASE: STUDYING SMOKING AND PROFESSIONAL DEPENDENCE

Аннотация

In this study, the relationship between social, clinical, and biochemical characteristics and the course of gastritis and peptic ulcer disease is analyzed, with particular emphasis on the influence of smoking on the development and duration of these diseases. The age distribution of patients, their social status, and the relationship between smoking and the duration of the illness are examined. The obtained data show that the 31-45 age group is most susceptible to gastroenterological diseases, with smoking having the greatest impact on the disease, which is confirmed by an increase in the duration of the disease and earlier onset of symptoms in smoking patients. It is important to note that professional activity also influences the development of these diseases, especially in office workers and technical specialists. Smoking is an important risk factor that worsens the clinical manifestations of gastritis and peptic ulcer disease. Goal. To assess the impact of social status, age, and smoking on the development and course of gastritis and peptic ulcer disease. Materials and methods. The retrospective study analyzed data from 100 patients (58 smokers and 42 non-smokers) diagnosed with gastritis or peptic ulcer disease between January and December 2024. The age of the patients ranged from 18 to 65 years. Data collection included questionnaires, clinical examinations, endoscopy, and laboratory tests. The survey included questions about the age of onset of the disease, duration of smoking, profession, and social status of patients. Clinical studies included physical examination, biochemical blood analysis, determination of gastric acid levels and tests for the presence of Helicobacter pylori. Results. The analysis showed that patients aged 31-45 years are most susceptible to gastroenterological diseases. Smoking was associated with an increased duration of the disease and an earlier onset of symptoms. Professional activity also influenced the development of diseases, especially among office workers and technical specialists. Conclusion. Smoking is a significant risk factor that worsens the clinical manifestations of gastritis and peptic ulcer disease. Age, social status, and professional activity also affect the course of these diseases. The findings emphasize the need for targeted prevention and treatment in at-risk groups.