MODERN METHODS OF CHOLESTEROL MANAGEMENT

Аннотация

Cholesterol management is pivotal in mitigating cardiovascular disease, a leading global cause of mortality. This article explores contemporary strategies for controlling cholesterol levels, integrating pharmacological advancements, lifestyle interventions, precision medicine, and digital health technologies. Statins, PCSK9 inhibitors, bempedoic acid, and inclisiran offer robust LDL-C reduction, while Mediterranean and Portfolio diets, exercise, and behavioral interventions enhance holistic care. Precision medicine, leveraging genetic testing and polygenic risk scores, tailors treatments, and digital tools like mobile apps and AI-driven algorithms improve adherence and monitoring. Global disparities in access to advanced therapies and adherence challenges are significant barriers, particularly in low- and middle-income countries. Emerging approaches, including gene editing, microbiome modulation, and nanotechnology, promise future innovations. The article underscores the need for equitable, multidisciplinary strategies to optimize cholesterol management and reduce cardiovascular risk worldwide.