RECURRENT APHTHOUS STOMATITIS

Аннотация

ABSTRACT. Recurrent aphthous stomatitis (RAS), commonly called "canker sores," is a perplexing oral condition characterized by the recurrent development of painful aphthous ulcers on non-keratinized oral mucous membranes. This condition poses a significant challenge to patients and healthcare professionals due to its uncertain etiology. Patients often report a family history of RAS, suggesting a genetic predisposition. Factors such as local trauma, stress, smoking cessation, anemia, and hematinic deficiency have also been linked to the occurrence of RAS. Gastrointestinal conditions like Crohn's disease, ulcerative colitis, and malabsorption diseases, including celiac disease, are associated with the development of oral aphthous ulcers. RAS is a possible clinical manifestation of more severe conditions like Behçet's disease or HIV infection, making early diagnosis and management critical.