PREVENTION OF MATERNAL AND FETAL COMPLICATIONS IN WOMEN UNDERGOING IN VITRO FERTILIZATION: A COMPREHENSIVE APPROACH

Аннотация

In vitro fertilization (IVF) has revolutionized the management of infertility; however, it is accompanied by an increased risk of maternal and fetal complications. These complications include ovarian hyperstimulation syndrome (OHSS), multiple gestations, preterm birth, low birth weight, and placental abnormalities. This prospective, multicenter observational study aimed to evaluate the effectiveness of a comprehensive prevention strategy in reducing such complications among women undergoing IVF. A total of 450 women scheduled for IVF were enrolled and managed using individualized ovarian stimulation protocols, elective single embryo transfer (eSET), intensive monitoring during the luteal phase, and patient-tailored counseling [1]. Maternal and fetal outcomes were compared with historical controls. Our findings demonstrated a significant reduction in the incidence of severe OHSS (from 8.2% to 3.1%, p < 0.01), multiple gestations (from 26.5% to 11.3%, p < 0.001), and preterm deliveries (from 19.4% to 9.8%, p = 0.02) in the intervention group. This study supports the use of an integrated, patient-centered approach in IVF management to prevent complications, thereby improvingbothmaternal and fetal outcomes [2]. Keywords: In vitro fertilization, maternal complications, fetal complications, prevention, ovarian hyperstimulation syndrome, single embryo transfer.