ARTERIAL HYPERTENSION IN PATIENTS WITH ANKYLOSING SPONDYLITIS AND PSORIATIC ARTHRITIS

Аннотация

The purpose of this work is to evaluate the occurrence of arterial hypertension (AH) and the frequency of new cases of its occurrence in patients with ankylosing spondylitis (AS) and psoriatic arthritis (PsA). Materials and methods. The data from a single-stage survey of patients with AS (n = 159) and PsA (n = 85) were analyzed. Another part of the work was the analysis of data from a 10‑year prospective follow-up patients with AS (n = 278) and PsA (n = 109) were followed. The patient data were compared with the results of the examination of healthy individuals (n = 150). The comparison of individuals from three groups by cardiovascular risk factors was performed. Results. According to the simultaneous analysis, the incidence of hypertension in AS and PsA was 48.7% and 67.5%, respectively (p = 0.03). Relative risk (RR) of hypertension in patients AS compared with healthy individuals was 2.22 (95% CI 1.59–3.1), the odds ratio (OR) was 3.34 (95% CI 2.1–5.3). The risk of hypertension in patients with PsA compared with people without spondyloarthritis (RR) was 3.08 (95% CI 2.19– 4.03). Conclusions. The risk of hypertension in patients with AS and PsA exceeds the risk of hypertension in healthy individuals. The incidence of hypertension and the frequency of new cases in PsA are higher than in AS. The number of new cases of hypertension increases over time in such a way that 10 years after diagnosis, every second patient has AS/PsA without cardiovascular diseases is at risk ofhypertension. Key words:arterial hypertension, cardiovascular risk, ankylosing spondylitis, ankylosing spondylitis,psoriatic arthritis