EROSIVE AND ULCERATIVE LESIONS OF THE GASTRODUODENAL ZONE IN PATIENTS WITH RHEUMATOID ARTHRITIS

Аннотация

Lesions of the gastroduodenal mucosa in patients with rheumatic diseases are widespread and have a significant impact on the course, prognosis, and treatment of the underlying disease. Factors that negatively affect the condition of the gastric and duodenal mucosa in rheumatic diseases, in particular rheumatoid arthritis, include inflammation of the mucous membrane of the digestive tract, vasculitis, and taking nonsteroidal anti-inflammatory drugs (NSAIDs)., concomitant diseases of the digestive tract, the manifestations or exacerbations of which are caused by the course of rheumatic diseases and the use of NSAIDs. The connection of lesions with reception has been revealed. NSAIDs, the severity of their occurrence, localization in the antrum of the stomach, the absence of an inflammatory shaft around the ulcerative defect, such a histological feature as foveolar hyperplasia of the mucous membrane, andsufficiently rapid healing after NSAID withdrawal. Key words:rheumatoid arthritis, gastroduodenal lesion, prognosis.