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РецензированоEN2021

Effects Of F-18 On KCL And Phenylephrine - Induced Contractions Of Rat Aorta

Contractions Of Rat Aorta · Abdisalim Zaripov · Adilbay Esimbetov (Karakalpak State University Named After Berdakh, Nukus, Uzbekistan) · Jo urnal Website: (Karakalpak State University Named After Berdakh, Nukus, Uzbekistan) · C opyright: Original Uzbekistan (Institute Of Biophysics And Biochemistry, National University Of Uzbekistan, Tashkent,) · Durdona Shokirova (Institute Of Biophysics And Biochemistry, National University Of Uzbekistan, Tashkent,) · Sherzod Zhurakulov (c ommons attributes Institute Of Biophysics And Biochemistry, National University Of Uzbekistan, Tashkent,)

The American Journal of Medical Sciences and Pharmaceutical Research · 03 · 146-156 · 2021

Аннотация

5 The mechanism of action of the alkaloid 1-(2´-bromine-4´,5´-dimethoxyphenyl) - 6,7-dimethoxy-1,2,3,4- tetrahydroisoquinoline (F-18) on the functional activity of smooth muscle cells of the rat aorta was studied. Isometric contraction activity was recorded using a Grass FT – 03 (Grass Instrument, USA) mechanotron. The relaxant effect of the F-18 alkaloid was found to be associated with blockade of Ca2 + (IP R) channels in the SR, along with voltage- dependent and receptor-operated Ca2+channels in 3 the aorta smooth muscle cell plasmalemma. KEYWORDS Rat aorta, vascular smooth muscle cells, vasorelaxation, Ca2+-channel.

Доказательный фрагмент

«5 The mechanism of action of the alkaloid 1-(2´-bromine-4´,5´-dimethoxyphenyl) - 6,7-dimethoxy-1,2,3,4- tetrahydroisoquinoline (F-18) on the functional activity of smooth muscle cells of the rat aorta was studied.»

Образец извлечения

Демо-превью

5 The mechanism of action of the alkaloid 1-(2´-bromine-4´,5´-dimethoxyphenyl) - 6,7-dimethoxy-1,2,3,4- tetrahydroisoquinoline (F-18) on the functional activity of smooth muscle cells of the rat aorta was studied. Полный текст публикации CiteX не хранит — доступ к первоисточнику открывается по DOI согласно лицензии издателя и выбранному плану.

doi.org/10.37547/TAJMSPR/Volume03Issue06-16
Цитирований
0
Тип
Журнал
Страна
Узбекистан
Ключевые слова
Rat aorta, vascular smooth muscle cells, vasorelaxation, Ca2+-channel, autoimmune thyroiditis, thyroid nodules, tumors., FNAB, cytology, thyroid gland
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