THE RELATIONSHIP BETWEEN CHRONIC KIDNEY DISEASE AND CARDIOVASCULAR DISEASE

Аннотация

Chronic Kidney Disease (CKD) and Cardiovascular Disease (CVD) share a strong bidirectional relationship, contributing to high morbidity and mortality worldwide. Insulin resistance (IR) has been identified as a significant factor exacerbating cardiovascular risks in renal patients, creating a vicious cycle of disease progression. This study explores the underlying pathophysiological mechanisms linking CKD and CVD, including inflammation, vascular dysfunction, and the renin-angiotensin-aldosterone system (RAAS). Additionally, common risk factors such as hypertension, diabetes, and dyslipidemia further accelerate the development of bothconditions. Keywords. Chronic Kidney Disease, Cardiovascular Disease, Insulin Resistance, Inflammation, Hypertension, RiskFactors, RAAS,diabetes.