CONTINUITY OF ANTICOAGULANT TREATMENT IN PATIENTS WITH COVID-19

Аннотация

anticoagulant therapy has gained importance during the COVID-19 pandemic due to changes in the blood coagulation system of patients, increasing the risk of thrombosis and embolism. This abstract provides a summary of the duration, indications, risks, and monitoring of anticoagulant therapy in patients with COVID-19. The disease COVID-19 causes changes in blood coagulation in many patients, which increases the risk of thrombotic events. Anticoagulants, such as low molecular weight heparins, play an important role in the prevention andtreatment of thrombosis. Key words: COVID-19, thrombosis, embolism, blood coagulation system, preventive treatment, drug doses, risk ofbleeding, medical professionals, duration oftreatment, patient, prevention. Today, it has become known to everyone that the coagulation system of the blood of patients infected with COVID-19 is one of the organs that suffer a lot of damage. This indicates that it is the main factor in the course of the disease and one of the important factors in the page291 INTERNATIONAL JOURNAL OF ARTIFICIAL INTELLIGENCE ISSN:2692-5206,ImpactFactor:12,23 AmericanAcademicpublishers,volume05,issue02,2025 Journal: https://www.academicpublishers.org/journals/index.php/ijai exacerbation of the disease. As a result of damage to the blood coagulation system of almost all patients, in addition to the development of many secondary diseases, many complications arise after these diseases, and this condition decreases the quality of life of patients, develops disability and reduces the ability to work or is completely incapacitated. cause. In a word, it is not wrong to say that managing the coagulation system in sick patients is disease management. [Accepted by the Ministry of Justice of the Republic of Uzbekistan on March 30, 2021, account number 8] These sanitary rules, norms and hygiene regulations (hereinafter - sanitary rules) medical organizations adapted to the treatment of COVID-19 infection and classification determines sanitary-hygiene andanti-epidemic measures toprevent infections. 2019 coronavirus infection (COVID-19) is an infectious disease caused by SARS-CoV-2, the severe acute respiratory syndrome coronavirus 2. The disease was first identified in Wuhan, China in 2019 and spread globally, causing the 2019-2020 coronavirus pandemic. The disease causes symptoms such as high fever, cough, and difficulty breathing. In somecases, musclepain, phlegm, and sore throat are observed. Although most people infected with the virus develop mild symptoms, in some patients the disease can lead to severe pneumonia and multiple organ failure. Among diagnosed cases, the mortality rate is on average 3.4 percent. Among people under 20 years old, this indicator is 0.2 percent, among people over 80 years old it is 15 percent. The virus is a type of disease that spreads from person to person through droplets produced when coughing and sneezing, similar to the flu. Although the virus is most contagious when a patient develops symptoms, it can be transmitted to others before symptoms appear. Symptoms usually appear within five days, but this period can last from 2 to 14 days. The main symptoms of the disease are fever, cough and shortness of breath. The disease can cause pneumonia and acute respiratory distress syndrome in the patient. There is currently no vaccine or medication for COVID-19. Disease management consists of symptomatic treatment and supportive therapy. To prevent the spread of the disease, it is recommended to wash hands, cover your mouth when you cough, and keep a distance from others (especially those who are not feeling well). Individuals suspected of having the virus are advised to self-isolate for 14 days. The pandemic has caused a number of socio-economic challenges globally, leading to the postponement or cancellation of sports and cultural events, and concerns about shortages of medicine, electronics, and food. information and conspiracy theories were published, cases of xenophobia and racism were observed in various countries, and panicked consumers were observed to buy goods such as toilet paper in large quantities. In July 2021, WHO Chairman Tedros Adhanom Ghebreyesus said that a vaccine-resistant strain of the coronavirus may appear as a result of vaccinations. In the treatment of patients suffering from corona virus disease, the use of anticoagulants is the main part of the standard of treatment. Patients suffering from coronavirus disease are treated in our center. In addition to the treatment of these patients, the effectiveness of the treatment is also checked and conclusions are drawn accordingly. During the treatment and observation, we witnessed that their coagulation system is damaged despite the use of anumber of anticoagulants. That is, it was felt that anticoagulants did not work after 7-8 days or their effect was insufficient, and this situation is reflected in the analyses. After conducting observations in several patients, we worked on how to