OTOSCLEROSIS: PATHOPHYSIOLOGY, CLINICAL MANIFESTATIONS, DIAGNOSIS, AND ADVANCES IN TREATMENT

Аннотация

Otosclerosis is a pathological bone remodeling disorder affecting the middle and inner ear. The term derives from "oto," meaning ear, and "sclerosis," referring to abnormal hardening. Initially described by Antonio Maria Valsalva in 1735 and later characterized pathologically by Adam Politzer in 1839, otosclerosis involves the replacement of the normal dense endochondral bone of the otic capsule with irregular spongy bone, which eventually hardens and leads to fixation of the stapes footplate.