Results of complex treatment of chronic rhinosinusitis in patients with community acquisited pneumonia

Аннотация

As world statistics show, 60% of patients with Shahlo Xamidullayevna Bakiyeva. (2025). Results of complex treatment of chronic rhinosinusitis develop bronchopulmonary chronic rhinosinusitis in patients with community acquisited pneumonia. pathology. According to foreign authors, the number of The American Journal of Medical Sciences and Pharmaceutical Research, 7(02), 37–40. https://doi.org/10.37547/tajmspr/Volume07Issue02-05 patients with chronic rhinosinusitis increases annually by 1.5-2%, and today more than 2/3 of inpatients are affected by this pathology. Due to the anatomical, physiological and complementary characteristics of the COPYRIGHT upper and lower respiratory tracts, there is a tendency © 2025 Original content from this work may be used under the terms of the creative commons attributes 4.0 License. towards a protracted course of rhinosinusitis, which in turn leads to the spread of the infectious process to the lower respiratory tract. It should be noted that existing foci of infection in the upper respiratory tract spread to the lower respiratory tract through microaspiration after an acute respiratory illness, which is the cause of the development of chronic bronchitis, bronchial asthma, and in particular pneumonia. It should be noted that despite the efforts of a number of specialists in the treatment of penmonia, in recent years there has been a significant increase in the incidence rate, as well as, unfortunately, an increase in mortality among people of various age groups. Keywords: Chronic rhinosinusitis, upper and lower respiratory tract, community-acquired pneumonia. Introduction: The results of medical statistics convincingly indicate an increase in the number of diseases of the nose, paranasal sinuses (PS) [1,2] and bronchopulmonary pathology [3]. The close anatomical and physiological connections between the upper and lower respiratory tracts are the reason that the increase in the incidence of rhinosinusitis has kept pace with the increase in the incidence of pulmonary diseases [4] and, in particular, community-acquired pneumonia (CAP). The American Journal of Medical Sciences and Pharmaceutical Research 37 https://www.theamericanjournals.com/index.php/tajmspr The American Journal of Medical Sciences and Pharmaceutical Research The incidence of pneumonia in Europe and North functions. Such a morphofunctional system ensures the America is 5–10 cases per 1 thousand population. The creation of the first barrier to the penetration of mortality rate from severe pneumonia reaches 10% infection. A subtle functional connection between the and continues to rise [3;5]. Pneumonia most often nasal cavity and paranasal sinuses with other organs and occurs in children, the elderly and chronic diseases of systems, primarily with the bronchopulmonary system, the respiratory system. It is believed that in almost any is obvious. acute respiratory viral infection, the paranasal sinuses METHODS are involved in the process to one degree or another A total of 102 patients with community-acquired [10]. Acute rhinosinusitis in 95% of cases is caused by pneumonia who were hospitalized in the pulmonology viruses; 5-7 days after the onset of ARVI, a bacterial department of the clinic of the Tashkent Medical process develops [6,7]. Under the influence of the virus Academy were examined. The age of patients ranged on the ciliated epithelium of the nasal cavity and from 18 to 60 years (average 39.1 ± 1.14 years), the paranasal sinuses, the epithelial cells lose their cilia, mean age of men was 34.1 ± 2.7 years, women 40.1 ± the epithelium becomes loose, and swelling of the 2.9 years, respectively (Table 1). mucous membrane develops. As a result of these processes, as well as the active release of pro- Distribution by gender: men - 41 people (40.2%), inflammatory mediators, an inflammatory reaction women - 61 people (59.8%), men - 41 people (40.2%). develops. The consequence of this is impaired aeration Complaints and the history of the development of the of the sinuses, inactivation of mucociliary clearance disease were clarified in detail in all patients, and the and accumulation of serous exudate in the lumen of general condition of the patients was examined. When the sinuses. Reducing the speed of mucociliary collecting an anamnesis, the timing of the onset of the transport allows prolonging the time of contact of disease was specified, the timing of the occurrence of pathogenic bacteria with the mucous membrane and relapses, their relationship with infectious diseases of promotes bacterial infection [8,11]. the upper respiratory system, and the presence of concomitant diseases of other organs were taken into The nasal cavity and paranasal sinuses are a highly account. organized structure, with a subtle and complex regulatory mechanism, which has many specific 19 18 20 15 15 13 13 15 10 7 5 2 0 18-30 yaers 31-40 yaers 41-50 yaers 51-60 yaers Table 1. Distribution of patients with CAP by sex (male/female) a