ASSESSMENT OF THE DYNAMICS OF HEPATIC ENCEPHALOPATHY IN PATIENTS WITH CIRRHOSIS BEFORE AND AFTER IN-HOSPITAL TREATMENT

Аннотация

Hepatic encephalopathy (HE) is a frequent complication of liver dysfunction, including acute liver failure and cirrhosis. HE presents with a sHEctrum of neuropsychiatric symptoms ranging from mild cognitive impairment to coma. The diagnosis of HE is based on the characteristic anamnestic, clinical and paraclinical findings and requires the exclusion of other causes of encephalopathy . Psychometric tests are widely used in clinical practice for the early diagnosis of HE: number-letter, number- line, handwriting, arithmetic etc. The sensitivity of psychometric tests in detecting HE is 70-80%. Although less severe, patients with minimal hepatic encephalopathy are at significant risk for impaired quality of life, including increased hospitalisation and progression to manifest HE. The main aim of our study is to compare and evaluate the extent and dynamics of HE in patients with cirrhosis before and after inpatient treatment. KEYWORDS Liver cirrhosis, hepatic encephalopathy, blood ammonia, hospital treatment. Volume 04 Issue 03-2022 7 The American Journal of Medical Sciences and Pharmaceutical Research (ISSN – 2689-1026) VOLUME 04 ISSUE 03 Pages: 7-11 SJIF IMPACT FACTOR (2020: 5. 286) (2021: 5. 64) (2022: 6. 319) OCLC – 1121105510 METADATA IF – 7.569 Publisher: The USA Journals