Состояние микрофлоры влагалища, кишечника и факторов местного иммунитета при некоторых TORCH-инфекциях, пути их коррекции

Аннотация

Subjects of the inquiry: 150 women with genital infection of reproductive age, 20 healthy women. Aim of the inquiry: To study microflora state of the large intestine and genital tract of women of reproductive tract suffering from TORCH-infections including mycoplasmosis and genital herpes in comparison with gardnerellosis and candidosis as well as to study character of vaginal local immunity and to develop methods of correction. Methods of investigation: Bacteriological and immunologic methods. The results achieved and their novelty: The dysbiotic changes were revealed in the patients both in the vaginal microflora and large intestinal microflora in the study women. However, in women with TORCH-infections these disorders were more profound in comparison with women without TORCH-infections that was characterized by changes in the parameters of local immunity. There has been proved necessity of introduction of therapeutic agents “Narine-plus”, lactobacterin “Orom” and immunocorrector “Viferon” into the common course of therapy. For the first tine there was studied large intestine and vaginal local immunity states in women with mycoplasmosis and genital herpes in complex. There have been developed effective methods of correction. Practical value: The evaluation of vaginal microflora, cervical canal and intestine has been made for the first time in genital herpes and mycoplasmosis as well as changes of the local immunity and developed scheme of correction of disorders revealed. Practical value: The evaluation of vaginal microflora, cervical canal and intestine has been made for the first time in genital herpes and mycoplasmosis as well as changes of the local immunity and developed scheme of correction of disorders revealed. Degree of embed and economic effectivity: The results of this work arc applied in the Tashkent Medical Academy in the studying process of students, as well as in the therapeutic and diagnostic activity of the gynecological department of 3-Clinic of Tashkent Medical Academy. The economic efficiency makes 3120 sum of one patient. Sphere of usage: Medicine: clinical microbiology, obstetrics and gynecology.