Разработка принципов предгравидарной подготовки женщин с невынашиванием беременности инфекционного генеза

Аннотация

Subjects of the inquiry: 230 women with presence in medical history two cases of abortion spontaneous. Aim of the inquiry, development and study of efficacy of pregravidity preparation of women with pregnancy interruption of infectious genesis. Methods of inquiry: ultrasonography investigation, IFA, PCR diagnosis, clinical, hormonal, bacteriologic, immunological, statistic and pathomorphological methods of examination. The results achieved and their novelty. Characteristic features of reproductive and somatic status have been studied in women suffering from pregnancy interruption of infectious genesis. On the basis of disorders revealed in the functioning of hypophyseal-ovarian system and immune status there has been shown necessity of complex pregravidity preparation. For the first time the estrogen preparation of plant origin Tefestrol was used as estrogen component in the hormonal replacement therapy. On the basis of the tests of functional diagnosis, ultrasonography of genital organs, as well as levels of steroid hormones and the results of endometrium morphological investigations efficacy of proposed pregravidity preparation for women with habitual abortion of infectious genesis. Practical value. The complex of pregravidity preparation allowing 1,6 times reduction of the rate of pregnancy interruption has been introduced into clinical practice. Degree of embed and economic effectively: the results of this research work have been applied in the practical work of Scientific-consultative polyclinic “Family and Marriage” of the Scientific Research Institute of Obstetrics and Gynecology, department of infertile family of the clinic of the Scientific Research Institute of Obstetrics and Gynecology of the Ministry of health of the Republic of Uzbekistan, in the educational process at the Chair of Obstetrics and Gynecology of Tashkent Pediatric Medical Institute, as well as branches of the Scientific Research Institute of Obstetrics and Gynecology of the Ministry of health of the Republic of Uzbekistan in Namangan, Karshi, Djizakh. On the basis of material of this dissertation there have been published methodical recommendations for pregravidity preparation of women with pregnancy interruption in the anamnesis of infectious genesis. Sphere of usage. Obstetrics and gynecology.