Комбинированное лечение нерезектабельного первичного рака печени

Аннотация

Subjects of research: Object of researches arc 90 patients with primary не-резектабсльными malignant defeats of a liver. Purpose of work: Improve the results of combined treatment of unrcsecta-blc primary form of liver cancer using intrao-pcratsionnoy intratumoral ethanol and subsequent degradation of poly-chemotherapy according to the scheme on the background of FAP immunotherapy. Methods of research: ultrasound, biochemical, enzyme immunoassay, radiological, morphological, statistical analysis of research results, and made magnetic resonance imaging, computer tomography. The results and their novelty: Modified technique of intraoperative local destruction, with the primary nerezcktabcl-govcmmcntal liver tumors, the novelty of which is to create a full-on saturation of the tumor with ethanol and necrotic ring by applecation with ethyl alcohol. An algorithm for combined treatment of unre-sectable primary liver cancer forms to increase the average life expectancy of patients by 66.2%, not the calling of heavy local and general reactions and complications, and does not lead to significant violations of the functional state of the liv-cr.echography, biochemical, иммуноферментные, radiological, morphology, statistical processing of results of a magnetic resonant tomography, a computer tomography. Practical value. The modified method provides direct access to the procedure for tumor destruction with ethyl followed by chemotherapy according to the scheme on the background of FAP antiviral and immunomodulatory therapies. Monitoring of the patient’s condition can be implemented with the help of the AFP tumor marker. The application of the algorithm of the combined method resulted in an increase in life expectancy of patients to ll,8±0,8 months, which is 66,2% higher than after monochemotherapy and 28,% after chemotherapy. Degree of embed and economic effectivity: The Basic results of disserta-tional work arc introduced in practice of work of branch of the Andjan regional oncological clinic, hospital surgical department of Andijan Medical Institute, the educational process of the department of clinical radiology, oncology and Phthisiology of Andijan Medical Institute. Field of application: Oncology.