Advantages of multimodal analgesia with paracetamol and ibuprofen in pediatric abdominal surgery

Аннотация

Enhancing the effectiveness of preoperative pain management in children remains a crucial task in modern pediatric surgery. Particular attention is given to the combination of paracetamol and ibuprofen, which, by acting on different pain mechanisms, provides powerful and prolonged analgesic effects with minimal side effects. Combining these drugs significantly reduces the need for opioids, thus decreasing the incidence of opioid-related complications such as respiratory depression and postoperative nausea [Friedrichsdorf SJ et al., 2015; Sing QW et al., 20171.