Применение фотодинамической терапии в лечение гнойно-воспалительных заболеваний мягких тканей

Аннотация

In the structure of post-operative complications surgical infection is between 32 and 75%. Our goal is to improve outcomes in patients with purulent-inflammatory diseases of soft tissues through the integrated application of PDT. Was examined and treated 327 patients with purulent wounds of soft tissues of different etiology and localization in age from 16 to 82 years. Depending on the treatment, the patients were divided into 2 groups: the 1st included 159 patients who were held tradi¬tsionnye common methods; in the 2nd group of 168 patients, which in combination with traditional methods of treatment used PDT with 0.05% methylene blue buffered solution. Method was used more often in superficial inflammatory diseases of the skin and soft tissues. The wound after standard surgical treatment and drying the photosensitizer was applied.Then, irradiation was carried out of the wound surface light emitter for photodynamic therapy. On day 5 after laser PDT virtually undetectable microflora. Tsitolo¬gicheskie study wound exudate after PDT with a photosensitizer methylene blue showed activation of phagocytosis, reduction of inflammatory infiltration of tissues, accelerating the growth and maturation of granulation tissue.