ANDROGEN-SECRETING ADRENAL TUMORS

Аннотация

The objective of this research was to study clinical peculiarities of androgen-secreting tumors in adrenals dependent on age and gender. Among the patients with various neoplasms in adrenals (n=282), who received out-patient and in-patient treatment in the Republican Specialized Scientific Practical Medical Center of Endocrinology of the Uzbekistan Public Healthcare Ministry within the period from 2000 to 2018, androgen-secreting tumors were diagnosed in 9(3.2%) patients: 3(33.3%) men and 6(66.7%) women aged from 1.7 to 34 years old. As well as in the other groups with adrenal neoplasms, there was double prevailing of women. However, correlation of separate age subgroups was significantly different. In this group of patients specific weight of children increased (55.6%) compared to adults under 44 years old (44.4%). In spite of similar etiopathogenetic basis analysis of clinical manifestations of adrenal androgen-secreting tumors in children and adults revealed some differences. So, performed analysis confirms the presence of several symptoms in children, symptoms which are not observed in adults. On the other hand, somatic disorders in adults are more expressed than in children. KEYWORDS Adrenal tumors, androgen-secreting tumors. Volume 02 Issue 04-2022 16 International Journal of Medical Sciences And Clinical Research (ISSN – 2771-2265) VOLUME 02 ISSUE 04 Pages: 16-22 SJIF IMPACT FACTOR (2022: 5. 705) OCLC – 1121105677 METADATA IF – 5.654 Publisher: Oscar Publishing Services Servi INTRODUCTION characteristics of adrenocortical carcinomas in patients of that age group. However, relative data of Adrenal androgen-secreting tumor is a rare pathology. adults population are diverse. Being hormonal active tumor of reticular area of adrenal cortex these neoplasms are characterized by The objective of the research was to study clinical increased production of androgens and its characteristics of adrenal androgen-secreting tumors metabolites. According to the basic series of dependent on age and gender. publications for the last 20 years the prevalence of