GRANULOMATOSIS WITH POLYANGIITIS: LITERATURE REVIEW

Аннотация

Wegener's granulomatosis (granulomatosis with polyangiitis) is a rare autoimmune disease characterized by vasculitis of small and medium-sized vessels and the formation of granulomas. Most often, Wegener's granulomatosis (WG) affects the upper respiratory tract, lungs, kidneys, and eyes. Without treatment, the disease progresses rapidly and leads to death. GV was first described at the end of the 19th century. The characteristic clinical picture of hepatitis B was described by the German pathologist Friedrich Wegener. After the reports of F. Wegener in 1936 and 1939. In cases of necrotizing vasculitis with granulomatous inflammation as a special nosological form of vasculitis, this disease became known as Wegener's granulomatosis. In 2006, F. Wegener’s connection with Nazism was discovered, and it was proposed to abandon the term “Wegener’s granulomatosis” in favor of the term “granulomatosis with polyangiitis,” which, in general, more reflects the modern view of the essence of this disease. The term "Wegener's granulomatosis", however, is today used along with the term "granulomatosis with polyangiitis". KEYWORDS Wegener's granulomatosis, vasculitis, polyangiitis. Volume 04 Issue 02-2024 15 International Journal of Medical Sciences And Clinical Research (ISSN – 2771-2265) VOLUME 04 ISSUE 02 PAGES: 15-19 SJIF IMPACT FACTOR (2021: 5. 694) (2022: 5. 893) (2023: 6. 184) OCLC – 1121105677 Publisher: Oscar Publishing Services Servi