BALANCING ACTS: UNVEILING THE HEPATO AND RENAL PROTECTIVE EFFECTS OF PHLORETIN IN STREPTOZOTOCIN-INDUCED DIABETIC RATS

Аннотация

This study investigates the potential hepatoprotective and renoprotective effects of phloretin in streptozotocin- induced diabetic rats. Phloretin, a natural dihydrochalcone flavonoid abundantly found in apples, exhibits antioxidant and anti-inflammatory properties. Streptozotocin-induced diabetes is associated with oxidative stress, inflammation, and organ damage, particularly in the liver and kidneys. The administration of phloretin aims to assess its ability to mitigate diabetes-induced hepatic and renal impairments. Our findings suggest that phloretin may serve as a guardian of health by conferring protection against diabetes-associated hepato and renal damage. KEYWORDS Phloretin, Streptozotocin, Diabetes, Hepatoprotective, Renoprotective, Oxidative Stress, Inflammation, Antioxidant, Dihydrochalcone, Streptozotocin-Induced Diabetic Rats.