PROTECTIVE EFFECTS OF ETHYL ACETATE ROOT EXTRACT OF TERMINALIA GLAUCESCENS ON DROSOPHILA MELANOGASTER AGAINST VIRULENT ASPERGILLUS SPECIES

Аннотация

This study investigates the protective effects of ethyl acetate root extract of Terminalia glaucescens on Drosophila melanogaster against virulent Aspergillus species. Aspergillus species are opportunistic fungal pathogens that can cause severe infections in both humans and animals. Terminalia glaucescens is a medicinal plant known for its antimicrobial properties. The objective of this research is to evaluate the potential of ethyl acetate root extract of Terminalia glaucescens in protecting Drosophila melanogaster against virulent Aspergillus species. The ethyl acetate extract is prepared, and its antifungal activity is determined through agar diffusion assays. Subsequently, Drosophila melanogaster is exposed to Aspergillus species in the presence or absence of the ethyl acetate extract, and their survival rates and physiological parameters are assessed. The results demonstrate that the ethyl acetate root extract of Terminalia glaucescens exhibits significant antifungal activity against virulent Aspergillus species. Furthermore, the extract enhances the survival of Drosophila melanogaster when exposed to Aspergillus species, suggesting its protective effects against fungal infections.