Изучение прогностической значимости онкопротеина her2/neu в оценке эффективности терапии у больных раком прямой кишки

Аннотация

The analysis of the prognostic significance of oncoprotein HER2/neu in 54 patients with rectal cancer with T3-4N0-1M0 stages of the disease. It has been shown that patients with relapsed disease, high expression of onkomarkers detected in 11.5% of cases, whereas in patients without relapses - in 3.5% of cases. At the same time, a small number of HER2/neu-positive primary adenocarcinoma of the rectum (15.0%) limits the prognos-tic significance of tumor marker for tumors of this localization. In order to develop effective models for the in-dividual prognosis of the disease, it is necessary to complete the use of various molecular markers that may contribute to a more accurate assessment of the potential of recurrent tumor