Разработкатаблетированной лекарственной формы антианемического действия наоснове местного сырья и оценка её качества

Аннотация

Subjects of research: mixtures of substances named “Mumifer” and “Ferascofol”, as well as tablet masses and tablets prepared from these mixtures and having the same names as mixtures. Purpose of work: “Mumifer” and “Ferascofol” tablets composition and technology development (elaboration), as well as their quality and biopharmaccutical parameters evaluation. Methods of research: method of mathematical planning the experiment, in vivo method, in vitro method, inductively coupled plasma mass-spcctromctric method etc. The results obtained and their novelty: Technological properties of mixtures of substances named “Mumifer” and “Ferascofol”, as well as quality parameters of model tablets prepared from these mixtures have been studied for the first time. Scientifically based compositions and technologies of “Mumifer” and “Ferascofol” tablets have been developed. On the base of appropriate researches results optimal amount of residual moisture in tablet mass has been established. “Mumifer” and “Ferascofol” tablets quality and biopharmaccutical parameters have been evaluated for the first time. The stability of active (medicinal) substances containing in tablets has been studied. Practical value: the results of researches conducted arc necessary for developing (elaborating) the projects of provisional (temporary) phannacopocial paper (article) and laboratory rcglamcnt for the recommended tablets. For instance the results of study of technological properties of substances mixtures named “Mumifer” and “Ferascofol” as well as quality parameters of model tablets prepared from these mixtures have a value in decision of matter (task) associated with tablets composition. Optimal residual moisture in tablet mass established as a result of a research is necessary for giving required technological properties to tablet masses and obtaining good quality tablets etc. Degree of embed and economic effectivity: the results of researches conducted have been included into the projects of provisional (temporary) pharmacopocial paper (article) and laboratory rcglamcnt developed (elaborated) for “Mumifer” and “Ferascofol” tablets. Field of application: pharmaceutical industry, medicine.