Заболевания диплококкоза и пастереллеза овец.

Аннотация

This article describes the mixed occurrence and prevalence of diplococcosis and pasteurellyoz among pet animals, their diagnosis, clinical symptoms, treatment and prevention methods. Keywords: microbiology, pasteurellosis, diplococcosis, epizootology, treatment, pathological anatomical changes, clinical signs, diagnostics, vaccine. Introduction: on the basis of the decree of the president of the Republic of Azerbaijan dated April 21, 2008 № PP-842 “on additional measures to encourage the reproduction of livestock products in the personal assistant, peasant and farmer farms, as well as to extend the production of livestock products”, aimed at increasing the employment and income of the rural population and the growth President Of The Republic Of UzbekistanM. In accordance with the decision of Mirziyoyev «on the strategy of actions for further development of the Republic of Uzbekistan»dated February 7, 2017, № PF- 5696, March 28, 2019 «on measures for radical improvement of the system of State Administration in the field of Veterinary and livestock», these studies will serve to a certain extent in the implementation of the tasks set. Results of the study: Diplococcosis is an infectious bacterial disease of Agriculture and wild animals (pathogen Diplococcus lanceolatum). The disease is more common in almost all seasons of the year, especially in winter and spring, threeraydi. The disease occurs mainly in animals in acute, acute, semi – acute forms, accompanied by inflammation of the lungs and intestines, sepsis, arthritis, lesions of the lymphatic system, and ends with 70-75% death. (A.A.Chepurov, A.V. Cherkasova). In infected animals, there is an increase in body temperature to 41 – 42 C, difficulty breathing, malaise, foamy – purulent fluid flows from the nose. When clinical signs are observed, the infected animals die if veterinary assistance is not shown on time. Large funds are spent on the treatment and prevention measures of sick animals. With diplococcosis, mainly children of calves, lambs and pigs get sick, and 70 – 75% die. Infected animals lag behind growth and development and are considered to be carriers of diplococci. Pasteurellosis is an infectious disease of agricultural animals and poultry, which occurs in extremely acute, acute and semi-acute forms (pathogen Pasteurella multus). Infected animals are accompanied by an increase in body temperature, coughing, bloody diarrhea, blood clots in the mucous membranes of the intestines. Clinical signs: in diseases that occur without intervention, clinical signs vary depending on the course of the disease and the virulence of the causative agent. When pathogens of diplococcosis and pasteurellosis meet in one organism, their clinical manifestations change. That is, in the body there is a state of exhaustion, fainting, refusal of food, and on the second day of the day there is wheezing, redness of the mucous membranes, an increase in body temperature to 42,0 – 42,5 C and bloody diarrhea. Patanatomic changes: an accurate diagnosis and recommendations for diseases are established based on the data of the initial Anamnesis, clinical symptoms, and then on the results of pathologic changes and bacteriological examinations. When the dead animal, infected with mixed disease, is pathologically ruptured, blood clots appear in the small intestine, sometimes even on the mucous membrane of the Shirdon with a dotted Speck, the heart is enlarged and the dotted blood vessels are clogged, and in the lungs the foam mucous blood accumulates in the cavities of the bronchi and alveoli. In addition to these, the main changes occur in the spleen, its size is relatively enlarged, and in the edges of the spleen, spotting, blood clots are observed. For bacteriological inspections GPB, GPA and 5% GPA with blood serum, 5% blood serum GPB transplanted samples to nutrient environments, +37,0 - +37,5 C is stored in a thermostat. During the observation period, 85 TECH-FEST-2022 International Multidisciplinary Conference Hosted from Manchester, England https://conferencea.org 25th May 2022 the overgrown cultures become turbid and grease is prepared from them and painted in a gram method. As a result of microscopic examination, diplococci and Pasteurella pathogens are distinguished. Due to these diseases, dotted blood transfusions and changes in them in internal parenchymatosis organs. Materials and methods: due to the above-mentioned problems, in the laboratory for the study of diseases of young moles of the Veterinary Research Institute, a polivalent experimental GOA form vaccine was developed using the cultures of local strains of pathogens of these diseases in order to prevent the disease of lambs diplococcosis and pasteurylosis. To determine the sterility of the vaccine produced, GPB, GPA, 5% GPA with blood serum, Kitt-Tarossi were sown to nutrient media and stored for 37,0 days in the thermostat at + 38,0 C - +10 C. To determine the harmlessness of this vaccine, 10 Head white mice