Дифференциальная диагностика и этапность хирургического лечения почечной формы первичного гиперпаратиреоидизма у детей

Аннотация

Subjects of research: for the period from 1992 to 2009 were examined in 2100 deteys ICD risk of developing PF PGPT were 305 children, of whom 52 children (2.47%) diagnosed with PF PGPT confirmed. Purpose of work: To improve the diagnosis and surgical treatment of renal forms of primary hyperparathyroidism in children Methods of research: clinical, biochemical, radioimmunolo-logical research, osteodensitometrichesky, ehoosteometrichesky, parathyroid scintigraphy, X-ray diffraction analysis of kidney stones and radioisotope methods. The results obtained and their novelty: It is shown that the differential diagnosis of IF PGPT based on the detection of violations of phosphorus-calcium metabolism and on the effectiveness of exercise testing acceptable to the child's body. Scientifically based criteria for the diagnosis and differential diagnosis of IF PGPT, resulting in a diagnostic algorithm. The terms and sequence of surgical procedures. Practical value: a diagnostic algorithm developed will allow the correct diagnosis in the early stages of the research PF PGPT children. On the basis of clinical and laboratory parameters and treatment strategy of patients PGPT PF, developed an algorithm by stages of surgery and recovery evaluation criteria that will help surgeons to obtain practical results of effective treatment for this disease. Postoperative treatment and rehabilitation of children with ICD and PF PGPT would improve the surgical intervention. Degree of embed and economic effectivity: a study put into practice clinic TashPMI, RSNAPTS Endocrinology Ministry of Health RU, City Clinical Hospital № 1 children and city children's surgical hospital № 2. Field of application: medicine (pediatrics), endocrinology, children surgery.