TARGETED THERAPY: ADVANCEMENTS IN DRUG DELIVERY SYSTEMS FOR SCHIZOPHRENIA TREATMENT

Аннотация

Schizophrenia is a complex psychiatric disorder characterized by a range of cognitive, emotional, and behavioral symptoms. Despite significant advancements in pharmacotherapy, challenges such as poor treatment adherence, limited efficacy, and adverse side effects remain prevalent. Drug delivery systems have emerged as promising approaches to overcome these challenges by improving drug targeting, bioavailability, and patient compliance. This review explores recent advancements in drug delivery systems tailored for the targeted treatment of schizophrenia. Various strategies, including nanoparticle-based formulations, lipid-based carriers, depot injections, and transdermal patches, are examined for their potential to enhance the delivery of antipsychotic medications to the brain while minimizing systemic side effects. Additionally, the review discusses the application of novel technologies, such as implantable devices and nanoscale drug carriers, in optimizing drug release kinetics and achieving sustained therapeutic effects. By highlighting recent developments and future prospects in drug delivery for schizophrenia treatment, this review aims to inform researchers, clinicians, and pharmaceutical developers about the evolving landscape of targeted therapy in mental health care. KEYWORDS Schizophrenia, Drug delivery systems, Nanoparticles, Lipid-based carriers, Depot injections, Transdermal patches, Implantable devices, Targeted therapy, Antipsychotic medications. Volume 04 Issue 04-2024 1 American Journal Of Biomedical Science & Pharmaceutical Innovation (ISSN – 2771-2753) VOLUME 04 ISSUE 04 PAGES: 1-7 SJIF IMPACT FACTOR (2022: 5. 705) (2023: 6.534) (2024: 7.7) OCLC – 1121105677 Publisher: Oscar Publishing Services Servi