CHRONIC KIDNEY DISEASE IN PATIENTS WITH ARTERIAL HYPERTENSION

Аннотация

INTRODUCTION The study included 133 patients with arterial hypertension of varying degrees - 3.8% in the first In recent years, the number of patients with end- case, 33.8% in the second, 62.4% with arterial stage chronic renal failure has increased hypertension of the third degree. 33.1% of the significantly. This is due to a significant increase in examined patients had clinical signs of chronic the prevalence of arterial hypertension coronary heart disease (II - II VC), coronary heart (hereinafter referred to as hypertension) in the disease, II VC and III VC were most often associated population of different countries [16 ،4 ،2 ،, 9]. with arterial hypertension grade 3-75%. Kidney diseases, not only cardiovascular diseases, respectively. but also serious cardiovascular diseases (myocardial infarction, stroke, etc.). Etc.) With According to the gender and age characteristics of arterial hypertension, there is a high probability of the patients, 77% of the total number of patients vascular complications, including the presence of studied were female, and the average age was 53.9 rhinocardial mechanisms that contribute to its years. The glomerular filtration rate was development.))), And this is the basis for the early determined by calculating a delayed formula based detection of renal dysfunction, timely correction of on the level of creatinine in the blood by age and the condition of patients in this category [3, 5, 7, 8]. sex. The aim of the study was to determine the The results of the study showed that regardless of diagnostic significance of assessing the glomerular the degree of arterial hypertension and its filtration rate using the extended formula in combination with different functional categories in patients with basal arterial hypertension, all groups studied, the level of creatinine in the depending on its degree and combination with blood did not exceed the standard values. chronic heart failure (hereinafter referred to as At the same time, in contrast to creatinine in the CHD). blood, the average glomerular filtration rate https://www.theamericanjournals.com/index.php/tajmspr 15 THE USA JOURNALS THE AMERICAN JOURNAL OF MEDICAL SCIENCES AND PHARMACEUTICAL RESEARCH (ISSN – 2689-1026) VOLUME 06 ISSUE05 decreased significantly and significantly, Compared with hypertension without clinically depending on the degree of arterial hypertension - significant signs of hypertension. Swiss franc. At from 96.1 degrees 1, 2.31 ml /min to 76.1 degrees the same time, this decrease was significant in 3, 1.3 ml / min, corresponding to the stage of renal patients with grade 3 arterial hypertension — by failure (moderate weakening) in patients with 14.4% at CHF II and by 25% at CHF III. grade 2 and 3 hypertension. The frequency of detection of renal insufficiency In patients with a combination of arterial also increased with the degree of hypertension and hypertension and CHF II - III VC, the decrease in the severity of CHF. Signs of impaired renal GFR was more significant: 78.85 for grade 2 arterial function (moderate decrease) increased by 37.3% hypertension - 1.1 ml/min and CHF II VC, 62.2 for and 28.3% in CHF II, the incidence of stage 3 grade 2 arterial hypertension - 1.1 mL/min and chronic kidney disease increased by 32% and 65.5 for CHF III VC - 1.4 ml/min for HSN II VC. 3 40.5% in grade 2 and 3 hypertension, respectively, arterial hypertension and CHF II VK , 57.3 , 1.1 ml / compared with hypertension without clinically min significant signs of CHF. With the introduction of the third Swiss franc, these figures increased even When assessing the frequency of detection of a further. That is, the detection of moderate renal decrease in the glomerular filtration rate, renal insufficiency in stage 2 hypertension increased by insufficiency was observed in 40% of patients with 34.5% - neither with grade 3 hypertension, nor grade 1 hypertension, 47.2% and 43.7% of patients with hypertension of the same degree, but without with grade 2 and 3 hypertension, respectively. pronounced clinical signs of CHF. The incidence of Grade 3 SP in 16.7% and 18.8% of patients with stage 3 chronic kidney disease increased by 50% arterial hypertension of grade 2 and 3, and 66.7%, respectively, in patients with stage 2 respectively. Before this stage, a decrease in the arterial hypertension and in stage 3, respectively, functional capacity of the kidneys is observed. compared with patients with arterial hypertension. In combination with arterial hypertension and CHF Conclusion: the assessment of GFR in the Midr (II-II VK), the incidence of moderate renal makes it possible to identify the first renal insufficiency (GFR = 90-60 ml/min) and stage 3 KD dysfunction already with grade 1 hypertension. In (GFR = 60-30 ml /min) increased directly addition, on October 2, even in combination with depending on both the degree of arterial CHF with pronounced clinical manifestations. 3. hypertension and the severity of CHF, which is a This allow