IMPROVING THE TREATMENT OF CALF DYSPEPSIA

Аннотация

INTRODUCTION such calves, an increase in the cost of treatment, A number of measures aimed at the intensive and the removal of calves into disrepair to development of animal husbandry are being replenish the herd in the future bring great carried out in our republic. Highly productive cows economic damage to farms [2,6,16]. According to were brought from abroad and are being cared for. Blazhnova M.V. (2004), 78.6% of calves were Violations of the rules for keeping and feeding cows infected with non-communicable diseases, of lead to metabolic disorders and the birth of which dyspepsia and gastrointestinal diseases hypotrophic calves. Dyspepsia and the death of https://www.theamericanjournals.com/index.php/tajvswd 6 THE USA JOURNALS THE AMERICAN JOURNAL OF VETERINARY SCIENCES AND WILDLIFE DISCOVERY (ISSN – 2689-0968) VOLUME 06 ISSUE03 accounted for 53.6%. According to Anokhin B.M., the field of therapeutic and preventive measures (2004), Kondrakhin I.P., (2004), Fazullin H.V. for diseases of the gastrointestinal tract is the use (2005), 60-70% of calves under the age of 10 days of probiotics, among which lactic acid, propionic suffer from gastrointestinal diseases and mortality acid and bifidobacteria are recognized as the most reaches 9.9%, while the body's natural resistance promising (Tarakanov B.V., 1987, Danilevskaya to this disease is low, hypogammaglobulinemia and N.V. 2006, Akimov D.A., 2015, Elenschleger A.A., hypotrophy of calves suffer [3,7,17,22]. 2020) [9,19]. In this regard, there has recently been a need to replace antibiotics with alternative, Calve dyspepsia is a disease with a complex environmentally friendly means of protecting etiology, and even after treatment, it has been animal health (Novitsky A., 2009, Ivanenko O.V. found that they are subject to secondary 2013, Jimmy L. Howard D. 1993). Despite the pathologies due to low immunity. (Gracheva O.A., progress made in the treatment and prevention of 2019, Volkova S.V., 2008, Novitsky A., 2009). neonatal calf dyspepsia, there remains a problem Eshburiev B.M. According to et al. (2017, 2018), associated with the development of effective, as dyspepsia disease is widespread among newborn well as cost-effective, treatment regimens for the calves in Uzbekistan, and the morbidity rate diseaseTherefore, scientists and practitioners of reaches 40-45% and the mortality rate reaches 30- veterinary medicine are faced with the task of 32% in some farms [4,10]. developing a comprehensive method of therapy Treatment of calf dyspepsia should be based on the and treatment regimens for dyspepsia in calves, the etiopathogenetic principle and should be aimed at introduction of which did not exclude the normalizing the digestive process, eliminating previously developed therapeutic and preventive dysbacteriosis, dehydration and intoxication. measures, but improved the existing ones [10,11]. To combat dysbacteriosis, antibiotics, Materials and Methods). Experiments were sulfonamides and nitrofuran preparations are conducted on calves up to 10 days old with used. Moreover, antibiotics must be selected after dyspepsia at "Akbar shox Shavkat" cattle farm in determining the sensitivity of the intestinal Pastdargom district of Samarkand region. For this, microflora to them. Traditional methods of treating 3 groups of 3 calves with dyspepsia were formed. sick calves with the use of antibacterial, The first and second experimental groups and the sulfanilamide and nitrofuran preparations do not third control group were designated. Calves in the always lead to a positive effect, and often have a first experimental group were treated as follows: negative effect on the obligate microflora and the they were starved for 8 hours, and during this time, immune status of newborn calves. Irrational 10 ml/kg (300) ml of Regidron solution was therapeutic tactics for the use of antibiotics, as well administered every hour. After the fasting period, as their unreasonable widespread use, leads to the 1/3 of the cow's milk (333 ml) + an equal amount emergence and growth of resistance to drugs of of warm physiological solution was added, and it pathogenic strains of microorganisms was rinsed 3 times a day. 40 ml of artificial gastric (Kamoshenkov A.R. 1998, Steiner T., 2006, Ivanov juice (1 g of pepsin, 1.5 NSl, 100 ml of distilled A.S., 2009, Khmylev A.G. ., 2019, Batrakov A. Ya., water) was injected 15 minutes before giving 2021,) [8,21]. colostrum. From the second day of treatment, Vetom 1.2 (Bacillus subtilis VKPM I-10641) To combat dehydration and restore disturbed probiotic 50mg/kg (2 times a day) was osmotic pressure, isotonic or hypertonic solutions administered every 8 hours until the symptoms of are administered. Hemotherapy, polyglobulins or diarrhea disappeared. gamma globulins are used intramuscularly as stimulating non-specific therapy for sick calves Calves in the second experimental group were (Kondrakhin I.P., 2005, Norboyev Q.N., Bakirov injected with Vetom 1.2 (Baci