Эволюция бронхита у молодых пациентов с точки зрения методов инструментального и бактериального исследования

Аннотация

We examined 128 patients with the age from 18 to 35 years. 20 individuals without preexisting lower respiratory tract diseases were chosen for comparison as a seperate group. They were clinically and endoscop-ically dignosed with a foreign body of the respiratory tract and underwent bronchoscopy with bronchoalveolar lavage for bacteriological analysis. 108 patients were diagnosed with recurrent bronchitis (ICD-10 J.40). These patients were further divided into 3 groups. We also performed the additional bacteriologic analysis of feces in order to determine the relationship between changes in the bronchial microbiocenosis under the influ-ence of the antibiotic therapy in comparison with the changes in the intestinal biocenosis. 80% of patients from the group III (no lactobacilli bacteria and bifidobacteria), who received antibiotics, demonstrated chages in bronchial microbiocenosis, which were statistically different (р 0,05) from the parameters of the microbioce-nosis in the group I (control), where antibiotics were administered in 47,5%. In the patients from the group II, where antibiotic therapy was used in 72,2% of patients, either lacto- or bifidobacteria were found. However these changes were not significantly different (p0,06) from the parameters of the group I, which may indicate the incompleteness of negative changes in the bronchial microbiocenosis. Based on the acquired data we found lactobacilli bacteria and bifidobacteria in bronchoalveolar lavage in 100% of examined individuals, who had no prior lower respiratory tract diseases