HEMATOLOGICAL EVALUATION OF MEDICALLY MANAGED PYOMETRA CASES IN DOGS

Аннотация

INTRODUCTION However, there is limited information available Pyometra is a common reproductive disorder in about the hematological changes that occur in dogs female dogs, characterized by the accumulation of with pyometra during medical treatment. pus in the uterus. It is a serious and potentially life- threatening condition that requires prompt Therefore, the aim of this study was to evaluate the diagnosis and treatment. Hematological evaluation hematological parameters of medically treated is an important diagnostic tool for assessing the cases of pyometra in dogs. The study was designed severity of pyometra and monitoring the to assess the changes in hematological parameters effectiveness of medical treatment. It provides before and after treatment, and to determine the valuable information about the overall health usefulness of hematological evaluation in the status of the animal and helps to identify any management of pyometra in dogs. The results of underlying complications or co-morbidities. this study may provide valuable insights into the effectiveness of medical treatment for pyometra in In recent years, there has been an increasing dogs and improve the management of this interest in the use of medical treatment for condition in clinical practice. pyometra in dogs, as an alternative to surgical intervention. Medical treatment involves the use of METHOD antibiotics and fluid therapy to control the A prospective study was conducted at a veterinary infection and improve the dog's condition. teaching hospital to evaluate the hematological https://www.theamericanjournals.com/index.php/tajvswd 1 THE USA JOURNALS THE AMERICAN JOURNAL OF VETERINARY SCIENCES AND WILDLIFE DISCOVERY (ISSN – 2689-0968) VOLUME 06 ISSUE03 parameters of medically treated cases of pyometra of pyometra was based on clinical signs, in dogs. A total of 30 female dogs diagnosed with ultrasonographic findings, and hematological pyometra were enrolled in the study. The diagnosis parameters. (PLT), mean corpuscular volume (MCV), mean The dogs were treated with a combination of corpuscular hemoglobin (MCH), and mean antibiotics, fluid therapy, and supportive care. The corpuscular hemoglobin concentration (MCHC), treatment protocol was standardized and followed were measured using an automated hematology for all dogs. Blood samples were collected from analyzer. The data obtained were analyzed using each dog at the time of diagnosis and at various descriptive statistics and repeated measures intervals during treatment (days 3, 7, and 14). analysis of variance (ANOVA) to determine the Hematological parameters, including white blood changes in hematological parameters during cell count (WBC), red blood cell count (RBC), treatment. A p-value of less than 0.05 was hemoglobin (Hb), hematocrit (HCT), platelet count considered statistically significant. https://www.theamericanjournals.com/index.php/tajvswd 2 THE USA JOURNALS THE AMERICAN JOURNAL OF VETERINARY SCIENCES AND WILDLIFE DISCOVERY (ISSN – 2689-0968) VOLUME 06 ISSUE03 diagnosis, indicating the presence of infection. The The study was approved by the institutional animal mean WBC count was 23.7 x 10^3/µL, which is ethics committee, and all dogs were treated in significantly higher than the normal reference accordance with the guidelines of the committee. range for dogs. Informed consent was obtained from the owners of the dogs before enrollment in the study. During treatment, there was a significant decrease in WBC count, with a mean count of 10.3 x 10^3/µL